J. James Frost

Applied Computational Technologies LLC design and develops software for life sciences application in radiation treatment planning for cancer therapy. The company was founded by Jay McClatchey and Richard Andrew Holland in 2003 and is headquartered in Stoystown, PA.

DiaKine Therapeutics, Inc. is a start-up biopharmaceutical company developing new, proprietary drugs for unmet medical needs in diabetes and complications related to diabetes. These drugs have the potential to restate the diabetes market by stopping the progression of diabetes and reversing damage already caused by the disease. Because of their unique immune modulating and anti-inflammatory properties, these therapies may potentially benefit people with type 1 and type 2 diabetes and represent a total available market opportunity of approximately $13 billion. The Company's lead compound, Lisofylline (LSF), has had an excellent safety profile in clinical trials to date. LSF works at the cellular level by improving the function of insulin producing islet cells and protecting them from damage and premature death caused when the body's immune system turns on itself. This autoimmune action is the cause of type 1 diabetes and Latent Autoimmune Diabetes in Adults (LADA), which combined affect approximately three million people in the U.S. About three million people with type 2 diabetes use insulin due to diminished insulin production and an increasing resistance to insulin. A primary focus of DiaKine's research and development is on its next generation of orally bioavailable immune modulators which have an improved spectrum of action to LSF. Two such compounds, DT22669 and DT23552, have been identified for further development and are examples of the extensive library of analogs and new structures in its patent portfolio that await discovery for future indications.

Nuclear Medicine Professionals, Inc. provides ancillary nuclear cardiac imaging services. The company was founded by John E. Millett in 2001 and is headquartered in Gainesville, FL.

Pet Center, Inc. manufactures pet food. It offers chicken and biscuits, chicken nibbles, chicken breast tenders, super chews, beef-n-hide, beef jerky, cowearz, bully sticks, quackers, lamb crunchys, lammy chews, porky wafers, pigearz. The company is headquartered in Los Angeles, CA.

BlueTree Allied Angels LLC (BlueTree Allied Angels) is a venture capital firm founded in 2003 by Catherine V. Mott and Tom Jones. The firm is headquartered in Wexford, Pennsylvania.