Jay Parrish

ARCH Venture Partners LLC is a Venture Capital firm founded in 1986. The firm is headquartered in Chicago with additional office in Dublin.

Rome Therapeutics, Inc. develops novel therapies for cancer and autoimmune diseases by harnessing the power of the repeatome-vast stretches of uncharted genetic materials. The company was founded by Rosana Kapeller and is headquartered in Cambridge, MA.

Pretzel Therapeutics, Inc. is an American biotechnology company that develops therapies by utilizing mitochondrial biology. Pretzel Therapeutics is based in an undisclosed location and has research facilities in another undisclosed location. The company aims to develop treatments that address the genetic causes of mitochondrial dysfunction. The company was founded by academic experts in mitochondrial biology and is supported by a world-class investor syndicate. Jay Parrish has been the CEO of the company since 2021.

Orbital Therapeutics, Inc. is a company based in Cambridge, MA that aims to enhance health by utilizing RNA-based medicines to treat human diseases in innovative ways. The company is building a platform that combines RNA technology delivery methods, data science, and automation to develop a portfolio of medicines focused on vaccines, immunomodulation, protein replacement, and regenerative medicine. The company was founded by Drew Weissman, John M. Maraganore, Kristina M. Burow, Ravindra Majeti, Giuseppe Ciaramella, Eugene W. Yeo, Howard Y. Chang, and Carol Suh, with Giuseppe Ciaramella serving as the CEO since incorporation.

Interline Therapeutics is an American drug discovery company that focuses on understanding protein communities to define molecular mechanisms of disease. The company is based in California and was incubated by Foresite Labs. Interline Therapeutics is developing new drugs that target key drivers of inflammation and cancer. The CEO of the company is Zachary Sweeney.

Guide Therapeutics, Inc. develops biophotonic technology platform for the early detection of disease that leads to cancer. The company was founded by James Dahlman and Cory Sago and is headquartered in Tucker, GA.

Abide Therapeutics, Inc. develops medicines that target serine hydrolases. Its approach is to selectively block serine hydrolases, potentially expanding this class of commercially validated enzymes as targets in a range of indications. The firm has a technology platform that exploits a chemoproteomics approach to selectively target serine hydrolases and rapidly identify target lead pairs. The company was founded by Alan B. Ezekowitz, Dale Boger, John Kennedy Clarke, Benjamin F. Cravatt, Todd Jones, Keith F. Lenden, and Paul R. Schimmel in 2011 and is headquartered in San Diego, CA.